Unpacking the Functions of the Endocannabinoid System: From Appetite Regulation to Mood Regulation The endocannabinoid system (ECS) is a complex signaling network that regulates various physiological and pathological processes in the human body. The ECS is composed of endocannabinoids, receptors, and enzymes that work together to maintain homeostasis in the body. The system is involved in a wide range of functions, from appetite regulation and pain sensation to immune response and mood regulation. Appetite Regulation: One of the key functions of the ECS is appetite regulation. Studies have shown that the activation of CB1 receptors in the hypothalamus stimulates appetite,…
Author: WebTeam
Irish MEP Luke ‘Ming’ Flanagan has called for the legalisation of cannabis as he shared a photo of his own cannabis plant growing in Belgium, where the plant is legal. Flanagan has previously admitted to safely growing the herb on his balcony and vaping it before going for a run. He argues that using legal cannabis means he knows exactly what he is using and does not give money to criminal gangs. Flanagan has been a long-time campaigner for cannabis legislation and has criticised the current laws that prohibit cannabis possession, which he believes have ruined people’s lives. Belgium has…
With the rise of black market commercial cannabis consumption in Northern Ireland, there has been growing concern about the safety and quality of the products available. Unlike other regions where cannabis is legal, such as Canada and some states in the US, there is no regulatory framework in place in Northern Ireland to ensure that the cannabis sold is free from harmful contaminants. This lack of regulation not only puts consumers at risk but also creates a lucrative market for organised crime groups. Unregulated Cannabis and its Risks The majority of cannabis consumed in Northern Ireland is black market commercial…
Remembering Dr. Raphael Mechoulam, a pioneering researcher in the field of cannabis and cannabinoid research, who passed away on March 6, 2023, at the age of 92. He is widely regarded as the “father of cannabis research” for his groundbreaking work in isolating and synthesizing THC, as well as his discovery of the endocannabinoid system. Mechoulam was born on November 5, 1930, in Sofia, Bulgaria, and moved to Israel with his family in 1949. He earned his Ph.D. in organic chemistry from the Hebrew University of Jerusalem in 1958 and began his research on cannabis in the 1960s. In 1964,…
Another fictional story about the day cannabis was legalised in Northern Ireland, just to give ye a wee bit of hope this fabulous day that is 420. Keep ‘er lit! On a sunny day in May 2025, Northern Ireland made history by legalising cannabis for sale, cultivation, and use. The decision brought an end to years of debate, activism, and criminalisation for cannabis users. Individuals over the age of 21 could now grow, buy, and sell cannabis without fear of legal repercussions. The news was met with jubilation from the cannabis community, as well as from advocates of drug law…
This is a fictional story for a bit of craic, set in the future about a cannabis grower named Alex, who decides to take a chance on outdoor cultivation in Northern Ireland due to the rising costs of indoor cultivation. In the year 2045, the world had changed in many ways. Climate change had become a reality, and many parts of the world were struggling with extreme weather events and rising sea levels. In Northern Ireland, the rising costs of electricity had made it almost impossible for cannabis growers to cultivate their crops indoors under artificial lights. As a result,…
The Synergistic Relationship Between CBD and THC in Edibles: What You Need to Know Cannabis edibles have become a popular way to consume cannabis, thanks to their discreet and long-lasting effects. However, recent research has shown that the relationship between CBD and THC in edibles is more complex than previously thought. One study, published in the Journal of Psychopharmacology, found that CBD can enhance the effects of THC when taken orally. The study assessed the effects of orally administered THC when combined with CBD and found that CBD enhanced the bioavailability and potency of THC. This means that CBD may…
Cannabis has become increasingly popular for its medicinal and recreational uses, but did you know that it can also be used for cooking? Cannabis-infused dishes, also known as edibles, are a delicious and discreet way to consume cannabis. In this beginner’s guide, we’ll discuss everything you need to know about cooking with cannabis, including how to make edibles and how to infuse cannabis into oils and other ingredients. Choosing the Right Strain for Cooking with Cannabis When it comes to cooking with cannabis, it’s important to choose the right strain. The two main types of cannabis strains are Indica and…
Cannabis has become increasingly popular in recent years, thanks to its potential therapeutic benefits. It has a range of medical applications, including pain relief, reducing inflammation, and easing anxiety. However, to access these benefits, you need to decarboxylate your cannabis. In this article, we will explain what decarboxylation is, why it’s important, and how to do it effectively. What is Decarboxylation? Decarboxylation is a chemical reaction that removes a carboxyl group from a molecule. In cannabis, this involves heating the plant material to activate the cannabinoids. Cannabinoids are the chemical compounds that give cannabis its therapeutic properties. However, they are…
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