A new study published in the journal PLOS One, as well as by the National Institute of Health, has found strong evidence that activation of our body’s cannabinoid receptors – something done naturally by cannabis – can treat osteoarthritis (OA), which, according to the study’s researchers, is “a prevalent disease accompanied by chronic, debilitating pain”. It’s the most common joint disorder. While studying the effects of cannabinoid receptor activation on OA-related pain, researchers found “new clinically relevant evidence that joint damage and spinal CB2 receptor expression are correlated combined with converging pre-clinical evidence that activation of CB2 receptors inhibits central…
Author: WebTeam
A new study published in the journal Neurourology and Urodynamics, and published online by the National Institute of Health, has found that our body’s endocannabinoid system is involved in regulating bladder function, and cannabinoids may provide treatment for urinary tract dysfunction. According to researchers; “Evidence suggests components of the endocannabinoid system are involved in regulation of bladder function, possibly at several levels of the micturition pathway.” They continue; “Amplification of endocannabinoid activity.. may be an attractive drug target in specific pathways involved in LUTS [lower urinary tract symptoms]“. They also note that; “Cannabinoids are reported to reduce sensory activity of…
A new study published by the National Institute of Health has found that cannabidivarin (CBDV) – a non-psychoactive compound found naturally in cannabis can effectively decrease the severity of seizures, and in many instances suppress them entirely. According to the study’s abstract; “Consistent with previous findings, CBDV significantly decreased PTZ-induced seizure severity (median: 3.25) and increased latency to the first sign of seizure.” They continue; “Furthermore, there were correlations between reductions of seizure severity and mRNA expression of Fos, Egr1, Arc, Ccl4 and Bdnf in the majority of brain regions in the CBDV+PTZ treated group. When CBDV treated animals were…
A new study being published in next month’s issue of the journal Biochemical Society Transactions, and published online early by the National Institute of Health, has found that the brain’s endocannabinoid system – which is activated through cannabis use – has neuroprotective and immunomodulatory capabilities, and may lead to the growth of stem cells. “Activation of cannabinoid receptors suppresses chronic inflammatory responses through the attenuation of pro-inflammatory mediators”, states the study’s abstract. “Moreover, the endocannabinoid system directs cell fate specification of NSCs (neural stem cells) in the CNS (central nervous sytem)”. According to researchers; “Pharmacological blockade of CB1 and/or CB2…
An intriguing new government funded study published by the Journal of Biological Chemistry has found that THC may actually alter certain genes in our body, which may result in a positive effect on a number of conditions, especially cancers and inflammatory diseases. Researchers using rat models found that THC positively altered 13 different microRNAs, including mir-690, which is strongly linked to inflammatory responses; the study claims that; “Among the differentially expressed, miRNA-690 was highly overexpressed in THC-MDSC (~16 fold)”. According to researchers; “Select miRNA such as mir-690 targeting genes involved in myeloid expansion and differentiation likely play crucial roles in…
A new study published in the journal PLOS One as well as the National Institute of Health has found that cannabinoids can be an effective treatment for acute lung injury, or acute respiratory distress syndrome (ARDS), which is a condition caused by damage or disease to the lungs, which is often life-threatening. The study, which was conducted by researchers at the University of São Paulo, found that: “MAGL inhibition, and consequently the increase in 2-AG levels [a naturally-occurring cannabinoid], produced anti-inflammatory effects in a murine model of LPS-induced ALI, a finding that was considered a consequence of the activation of…
In an unprecedented turn of events, Sensi Seeds founder Ben Dronkers was interrupted by High Times security during his seminar at the Cannabis Cup expo today, as he threw small bags of cannabis into the audience. By this time, Ben realised what was occurring and addressed the crowd and the man — “there’s no law against sharing cannabis!” Although Sensi Seeds understands the trepidation of High Times, especially following the unexpected bust in 2011, each bag, freely given, contained only one gram of cannabis. Given the stringent security present on the doors of the venue checking that each person had…
Reggae, ganja and the name of Bob Marley are, for many people, practically synonymous. The man who brought the rhythms of Jamaica and the preferred sacrament of the Rastafari movement to a grateful worldwide audience will probably never be forgotten, unless the human race ceases to plant cannabis seeds and listen to music. Naturally, this legendary man has his own strain of cannabis – Marley’s Collie from Sensi Seeds. This well-respected Amsterdam seed company took several years to create a strain worthy of Bob Marley’s name. Initially, a select group of tropical Jamaican Sativas were bred and refined until a…
Petition: No more Death Penalty for Cannabis! Spare Thitima Khongnun’s life! On the 20th of October 2011, Thitima Khongnun, a single mother from Thailand, was caught in Alor Setar with 18,172 grams of Cannabis, because of her crime, the mother of two have been sentenced by the Malaysian high court to the death penalty on the 2nd of July 2013. Click here to sign the petition to spare Thitima Khongnun’s life Regardless of her intent, it is absolutely immoral to rob the two children of the life of their mother. Especially since the crime is only for trafficking marijuana. We,…
Boston, MA: An estimated one-in-six patients with inflammatory bowel disease (IBD) report using cannabis therapeutically, according to survey data published in the journal Inflammatory Bowel Diseases. Researchers assessed survey responses from 292 IBD patients seeking treatment at the Brigham and Women’s Hospital, Crohn’s and Colitis Center in Boston, Massachusetts. Investigators reported that over half of all respondents possessed first-hand experience with cannabis, and that just over 16 percent had used it to mitigate symptoms of the disease. “We found that approximately 16.4 percent of patients with IBD cared for at a tertiary referral center have used marijuana to treat their…
